CJC-1295 + Ipamorelin
CJC-1295 (no DAC) + Ipamorelin blend
What is CJC-1295 + Ipamorelin?
CJC-1295 + Ipamorelin: Popular 'beginner GH stack' combining a GHRH analogue (Mod GRF 1-29) with a ghrelin-receptor agonist (ipamorelin). The sources cited here most often discuss it for: Amplified GH pulses, theoretical; Better sleep, anecdotal; Body recomposition, anecdotal. Evidence label: Unstudied.
- Type
- Blend
- Family
- Growth Hormone Axis
- Evidence label
- Unstudied (1 of 5)
- Regulatory status
- FDA lists CJC-1295 among compounding nominations that were withdrawn from Category 2, while ipamorelin acetate remains in 503B Category 2 for significant safety risks.
- Goals discussed
- Hormones & Fertility, Sleep, Muscle & Tone, Fat Loss & Metabolism, Healing & Recovery
- Also called
- CJC/Ipa, CJC Ipa, CJC-1295 Ipamorelin, cjc+ipa, ipam/cjc, power combo
- Last reviewed
- 2026-10-11
- Popular 'beginner GH stack' combining a GHRH analogue (Mod GRF 1-29) with a ghrelin-receptor agonist (ipamorelin); the two act on different pituitary pathways to amplify a GH pulse; neither component FDA-approved and the blend has never been tested in a human trial.12
Usually means CJC-1295 without DAC (also called Mod GRF 1-29) combined with ipamorelin. CJC-1295 with DAC is a different, longer-acting molecule, and product labels do not always say which one is used.
Regulatory status FDA lists CJC-1295 among compounding nominations that were withdrawn from Category 2, while ipamorelin acetate remains in 503B Category 2 for significant safety risks. 3
Names as used in gyms, forums and gray-market listings. Reported, not endorsed; stacks have not been studied as combinations.
FDA has identified serious adverse events associated with CJC-1295 including increased heart rate and systemic vasodilatory reaction.
FDA safety summary for the CJC-1295 component, written when it was nominated for compounding; the blend itself has never been tested in a trial.
What is CJC-1295 + Ipamorelin researched for?
The three outcomes most discussed for CJC-1295 + Ipamorelin in the sources below, as those sources report them. humanpeptides.fyi makes no claims of its own: a listed benefit can be unproven or can have failed in trials, and the label on each line says which.
What do researchers and users say about CJC-1295 + Ipamorelin?
The days I don’t take it, I can’t sleep, days I do, I sleep like a rock.
Single user's self-report in a Reddit thread; not verified and not a controlled observation.
Interesting. I find it damages my sleep. It pushes me too far into deep sleep, and the lack of REM means I wake up groggy and sluggish.
A different user in the same thread reporting the opposite sleep effect; anecdotal.
What side effects of CJC-1295 + Ipamorelin are reported?
- Water retention, facial puffiness, hunger, injection reactions, sleep disruptionanecdotal9
- FDA Category 2 safety concerns for ipamorelin3
- FDA has linked the CJC-1295 component to serious adverse events including increased heart rate and a systemic vasodilatory reaction.FDA safety review3
- Some users report a higher overnight heart rate and lower heart rate variability, or waking in the middle of the night.anecdotal6
- Both components are prohibited in tested sport under the WADA list.regulatory10
What do peptide guides say about CJC-1295 + Ipamorelin?
- Dr. Axe Dr. Axe rates the CJC-1295/ipamorelin pairing as insufficient evidence, noting the only cited human study tested CJC-1295 alone and that measured hormone rises do not prove a clinical benefit. 11
- PepEdHub PepEdHub catalogs the pairing as a growth hormone combination under the names CJC-1295 Ipamorelin, CJC Ipa and CJC/Ipa; its page summary says injected or animal data do not establish outcomes for intranasal combination products. 12
- Seek Peptides Seek Peptides calls ipamorelin plus CJC-1295 the gold standard stack for muscle and anti-aging goals, while flagging a theoretical tumor-growth concern with growth-hormone-releasing peptides in active cancer. 13
- McDermott Will & Schulte A July 2026 law-firm analysis reports the Ohio Board of Pharmacy has taken enforcement action, sometimes summary suspension, against pharmacies compounding peptides such as CJC/Ipamorelin that lack federal compounding authorization. 14
What does the research say, system by system?
How strong is the evidence for CJC-1295 + Ipamorelin?
No human trials of the blend; component pharmacology + anecdotal
No direct studies of this product or blend. Anecdote and component data only. How tiers work
Questions about CJC-1295 + Ipamorelin
What is CJC-1295 + Ipamorelin?
Popular 'beginner GH stack' combining a GHRH analogue (Mod GRF 1-29) with a ghrelin-receptor agonist (ipamorelin). Usually means CJC-1295 without DAC (also called Mod GRF 1-29) combined with ipamorelin. CJC-1295 with DAC is a different, longer-acting molecule, and product labels do not always say which one is used.
Is CJC-1295 + Ipamorelin FDA-approved?
FDA lists CJC-1295 among compounding nominations that were withdrawn from Category 2, while ipamorelin acetate remains in 503B Category 2 for significant safety risks.
What is CJC-1295 + Ipamorelin researched for?
The sources cited on this page most often discuss three outcomes: Amplified GH pulses, theoretical; Better sleep, anecdotal; Body recomposition, anecdotal. Each line above shows what the source reports and how strong that evidence is.
What side effects of CJC-1295 + Ipamorelin are reported?
Reported in the cited sources: Water retention, facial puffiness, hunger, injection reactions, sleep disruption; FDA Category 2 safety concerns for ipamorelin; FDA has linked the CJC-1295 component to serious adverse events including increased heart rate and a systemic vasodilatory reaction. The list is not complete, and few listed risks does not mean a compound is safe.
How strong is the evidence for CJC-1295 + Ipamorelin?
Evidence label: Unstudied. No human trials of the blend; component pharmacology + anecdotal.
What else is CJC-1295 + Ipamorelin called?
Names used for it include CJC/Ipa, CJC Ipa, CJC-1295 Ipamorelin, cjc+ipa, ipam/cjc, power combo.
Does humanpeptides.fyi recommend CJC-1295 + Ipamorelin?
No. humanpeptides.fyi makes no claims and no recommendations of its own. It summarizes and links to what others have published and posted. Nothing here is medical advice; talk to a licensed clinician.